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Dietary Fish Oil Effects on Weight Loss
Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects was the title of the research that was published Integrative Cancer Therapies in December of 2003. The principal researchers were Trevor A Mori, Danny Q Bao, Valerie Burke, Ian B Puddey, Gerald F Watts and Lawrence J Beilin. They conducted their research at The Department of Medicine, The University of Western Australia and The West Australian Heart Research Institute.
The background of the study was obesity in hypertensive patients is associated with dyslipidemia and insulin resistance, both of which are improved by weight control. n-3 Fatty acids have diverse effects on mechanisms underlying atherosclerosis, including a decrease in serum triacylglycerols and an increase in HDL2 cholesterol. The objective was to examine whether dietary fish enhances the effects of weight loss on serum lipids, glucose, and insulin in 69 overweight, treated hypertensive patients.
Overweight patients being treated for hypertension were randomly assigned to either a daily fish meal (3.65 g n-3 fatty acids), a weight-loss regimen, the 2 regimens combined, or a control group for 16 wk. Sixty-three subjects completed the study. Weight decreased with energy restriction. Weight loss decreased fasting insulin and the area under the curve for insulin and glucose during an oral-glucose-tolerance test. The greatest decrease occurred in the fish + weight-loss group. There was no independent effect of fish on glucose or insulin.
Fish increased HDL2 cholesterol and decreased HDL3 cholesterol without altering total, LDL, or HDL cholesterol. Weight loss had no effect on these variables. Fasting triacylglycerols fell significantly with fish consumption (29%) and weight loss (26%). The fish + weight-loss group showed the greatest improvement in lipids: triacylglycerols decreased by 38% and HDL2 cholesterol increased by 24% compared with the control group
The final conclusions were, incorporating a daily fish meal into a weight-loss regimen was more effective than either measure alone at improving glucose-insulin metabolism and dyslipidemia. Cardiovascular risk is likely to be substantially reduced in overweight hypertensive patients with a weight-loss program incorporating fish meals rich in n-3 fatty acids
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For free friendly advice or to order over the phone with a card call: 01772 883950
Omega 3 fish oils Pure EPA is available exclusively from mind 1st.
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