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Cellular absorption omega 3
In this study five normolipemic subjects received three test meals containing 28 grams n- 3 (omega-3) fatty acids provided as either of the following: 1) triglycerides, 2) ethyl esters, and 3) ethyl esters + 12 grams of olive oil. The control meal contained olive oil.
When equivalent amounts of fat were given to the test subjects, the increase in chylomicron and plasma triglycerides observed was similar; n-3 fatty acid contents were also similar after n-3 fatty acid intake as ethyl esters or triglycerides. Ethyl esters alone were well absorbed and produced similar n-3 fatty acid responses in plasma triglycerides and chylomicrons.
At 24 hours after the test subjects consumed the n-3 fatty acid-containing meals, the fatty acid plasma concentration of these acids was similar. This study showed that n-3 fatty acids in fish oil, given as ethyl esters or triglycerides, were equally well absorbed. Eicosapentaenoic and docosahexaenoic acids were also equally absorbed.
This was a study that was conducted at The Department of Medicine, Oregon Health Sciences University, Portland. The principal researchers on this study were A Nordoy, L Barstad, WE Connor and L Hatcher and it was entitled: Absorption of the n-3 eicosapentaenoic and docosahexaenoic acids as ethyl esters and triglycerides.
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