![]() |
||||||||||||
|
||||||||||||
A study took place at Institute of Internal Medicine and Metabolic Diseases, Federico II University, Naples, Italy and was published in the November 19th edition of Diabetes Care. A team of researchers including principal researcher AA. Rivelese set out to evaluate the long-term (6-month) effects of moderate fish oil supplementation on insulin sensitivity and plasma lipoproteins in NIDDM patients with hypertriglyceridemia.
The study structure was performed according to a randomized double-blind placebo-controlled design with a parallel group sequence. After a washout period of 4 weeks and a run-in period of 3 weeks, 16 NIDDM patients with hypertriglyceridemia were randomly assigned to either fish oil (2.7 g/day eicosapentaenoic plus docosahexaenoic acid for 2 months, then 1.7 g/day for 4 more months) or a placebo.
The subjects diet and hypoglycemic drugs remained unchanged throughout the entire experiment. In the group treated with fish oil compared with the baseline, there was: 1) a significant reduction in both plasma TG and VLDL-TG, without significant changes in blood glucose control; 2) a significant reduction in fasting NEFA concentrations; and 3) a significant enrichment in long-chain omega-3 fatty acids of erythrocyte membrane phospholipids.
In the placebo group, there were no changes in any of the variables analyzed. The insulin-mediated glucose uptake was unchanged in both groups. The researchers concluded that in NIDDM patients with hypertriglyceridemia, moderate amounts of fish oil induce a long-term significant reduction in plasma triglycerides, VLDL triglycerides, and NEFA and a significant enrichment in the erythrocyte phospholipids content of long-chain omega-3 fatty acids, without deteriorating blood glucose control. However, this amount of omega-3 fatty acids was unable to improve insulin sensitivity in this group of patients.Overall Health Benefits of Fish Oil
Omega-3 is essential for the growth and functional development of the brain in infants. Omega-3 is also required for maintenance of normal brain function in adults. The inclusion of plentiful Omega-3 in the diet improves learning ability, whereas deficiencies of Omega-3 are associated with deficits in learning. Omega-3 is taken up by the brain in preference to other fatty acids. The turnover of Omega-3 in the brain is very fast, more so than is generally realized. The visual acuity of healthy, full-term, formula-fed infants is increased when their formula includes Omega-3.
During the last 50 years, many infants have been fed formula diets lacking omega-3 fatty acids and these deficiencies are associated with fetal alcohol syndrome, attention deficit hyperactivity disorder, cystic fibrosis, phenylketonuria, unipolar depression, aggressive hostility, and adrenoleukodystrophy. Decreases in Omega-3 fatty acids in the brain are associated with cognitive decline during aging and with onset of sporadic Alzheimer disease.
The leading cause of death in western nations is cardiovascular disease. Epidemiological studies have shown a strong correlation between fish consumption and reduction in sudden death from myocardial infarction. The reduction is approximately 50% with 200 mg day (-1) of Omega-3 fatty acids from fish. Omega-3 is the active component in fish. Not only does fish oil reduce triglycerides in the blood and decrease thrombosis, but it also helps prevent cardiac arrhythmias.
The association of Omega-3 fatty acid deficiency with depression is the reason for the robust positive correlation between depression and myocardial infarction. Patients with cardiovascular disease or Type II diabetes are often advised to adopt a low-fat diet with a high proportion of carbohydrate. A study with women shows that this type of diet increases plasma triglycerides and the severity of Type II diabetes and coronary heart disease. Necessary Omega-3 is present in fatty fish (salmon, tuna, and mackerel) and mother's milk, but is present at low levels in meat and eggs, and is not usually present in infant formulas. EPA, another long-chain n-3 fatty acid, is also present in fatty fish. The shorter chain n-3 fatty acid, alpha-linolenic acid, is not converted very well in man. These long chain n-3 fatty acids (also known as omega-3 fatty acids) are now becoming available in some foods, especially infant formula and eggs in Europe and Japan.
These opposite effects are also seen with inflammation, particularly with rheumatoid arthritis, and with asthma. Omega-3 has a positive effect on diseases such as hypertension, arthritis, atherosclerosis, depression, adult-onset diabetes mellitus, myocardial infarction, thrombosis, and some cancers.Omega 3 fish oils Pure EPA is available exclusively from mind 1st.
|
|
Mind1st Information Line: 01772 883950
mind | whats in Pure EPA | omega 3 info | fish oil capsules | flaxseed fish oil | omega 3 fish oil | pure EPA | EPA | fish oils and how to grade them | fish oil supplements | essential fatty acids | omega 3 fatty acid | eicosapentaenoic acid | fish oils | pregnancy | pharmaceutical grade fish oil | Epa fish oil | Omega 3 fish oil EPA and DHA | IBS symptom relief | borage oil | Fish oil cholesterol | fish oil pill tablet | fish oil vitamin | fish oil side effects | benefit of fish oil | vegepa | omega 3 fish oil capsule | dosage | vitamin e | ADHD | arthritis | pregnancy| depression | weight loss | children | bipolar | fatty acid | benefit of fish oil | health benefits | fischöl | acne | DHA | fish oil and PMS | diabetes | allergy | heart disease | deep sea fish | ADD | ultra refined fish oil | concentrate purity | information | supplements and mercury m | anxiety | blood pressure | healthy skin | OCD | liver disease | fish oil dietary supplement | omega 3 6 9 | Request a link | weight loss programme
© 2008 www.mind1st.co.uk fish
oil
A Nurank Corp company www.nurankcorp.com