
	Omega 3 Info
	Antioxidant Omega 3
	Beef CLA
	Biochemistry Reaction
	Bipolar
	Chemical Configuration
	Chemical Formula
	Cooking oils
	Daily intake
	Difference Omega 3 and Omega 6
	Directions for Taking Omega 3
	Essential Nutrients
	Excess omega 3
	Fat, Protein, Carbohydrate
	Hemp Amount of Omega 3
	Kidney Functions Omega 3
	Nile Perch
	Olive Oil
	Algae Oil
	Omega Ratios
	Benefit Fish - Flax
	Eczema
	Omega 3 Deficiency Food Digestion / Gluten intolerance
	Aches and Pains
	Canine Renal Failure
	Omega 3 Fatty Acids for Dogs
	Fish Oil Linolenic Acid Content

Biochemistry Reaction Omega 3 EPA DHA

Through one biochemistry reaction, omega 3 EPA and DHA are manufactured within our bodies. Through a different biochemistry reaction, omega 3 EPA and DHA are made into other compounds that are metabolically active.

Biochemical Manufacture of EPA and DHA

There are three important omega 3 fatty acids in the human body: ALA, EPA and DHA. ALA is primarily found in plant sources, such as green leafy vegetables and certain plant oils. We can consume EPA and DHA, primarily from marine sources, and our bodies can also manufacture them from ALA.

Three specific enzymes—two desaturase enzymes and elongase—are required to convert ALA into EPA. Further biochemical processes convert EPA into DHA.

The same enzymes used in the biochemical conversion of omega 3 oils are also used in the biochemical conversion of omega 6 oils. Linoleic acid is converted to arachadonic acid using the same two desaturase enzymes and elongase.

Biochemical Conversion of EPA and DHA
Cyclooxygenase (COX) enzymes convert EPA and DHA into prostaglandins and thromboxanes. The omega 3 prostaglandins are anti-inflammatory, and the omeg 3 thromboxanes are anti-clotting.

Lipoxygenase (LOX) enzymes convert EPA and DHA into leukotrienes. Again, the omega 3 leukotrienes are anti-inflammatory.

Recent research shows that COX and LOX enzymes also convert DHA to other substances that are neuroprotectins. These substances are thought to have a protective influence on nervous tissue, and they may be involved in cognitive activities such as learning and memory.

The same COX and LOX enzymes also convert the omega 6 acid arachadonic acid into prostaglandins, thromboxanes and leukotrienes. The omega 6 biochemicals are pro-inflammatory and pro-clotting.

Biochemical Competition

Because they use the same enzymes, the omega 3 and omega 6 reactions are said to be competitive. They compete for the enzymes. Whether pro-inflammation or anti-inflammation dominates depends on which group gets more of the enzymes. That depends on:

The biochemical environment
The relative amounts of omega 3 and omega 6

Inflammation is a protective response to cell damage. Damaged cells leak substances that change the biochemical environment so that arachadonic acid grabs the enzymes faster.

Unfortunately, the normal Western diet of the past half century or so has much more omega 6 than omega 3 in it. That results in a chronic pro-inflammatory state, and may be the cause of many of the health problems we experience in developed nations.

Omega 3 fish oils Pure EPA is available exclusively from mind 1st.

Mind1st Information Line: 01772 883950